Taken against her will, Dana Harker was transformed into a human-cat hybrid known as Nightcat. With police detective David Rayner at her side, she patrols the streets of Grace City, keeping the residents safe from whatever evil lurks in the shadows.

Grace City, the first frontier. These are the adventures of the mutant cat hybrid Nightcat. Her continuing mission: To explore the depths of criminal stupidity, To seek out new miscreants and new felonious organizations To boldly go where she has likely gone before.

You know, because criminal activity tends to reoccur in certain areas.