According to World Health Organizations equity can be defined as "the absence of avoidable differences among groups of people, whether those groups are defined socially, economically, demographically, or geographically." The principles of health equity include insuring equal access, utilization and health outcomes for all populations seeking healthcare. It is important to have a global approach in solving these issues to create healthier communities. The theme of this issues focus on disparities faced by marginalized groups in the United States and abroad. Through creative works, innovative research, and thoughtful commentary, our authors explore challenges faced in achieving health equity and assert their opinions on the theme.