Presents critical concepts, principles, and rationale to improve, update, and adapt antimicrobial utilization to maximize outcomes and minimize resistance and costs. This book describes the economics of drug-resistant infections and the management of antimicrobial use, and provides information on methods to optimize the selection. " The editors are to be congratulated for assembling an expert group of authors to write the 19 chapters that make up this treatise?.a good resource by which to ensure the appropriate use of antimicrobial therapy."-New England Journal of Medicine