Reviews the progress in all key areas of natural product chemistry since the first edition was published in 1983. The most significant advances are highlighted over a wide field of chemistry, structure, synthesis and biosynthesis.
1 Carbohydrates.- 1.1 Introduction.- 1.2 Recent developments in O-glycosidation methodology.- 1.3 Recent developments in C-glycoside synthesis.- 1.4 Synthesis of antibiotic sugars.- 1.5 Use of carbohydrates as chiral templates and reagents for asymmetric synthesis.- 1.6 Use of carbohydrates as chiral starting materials for the synthesis of enantiomerically pure natural products.- References.- 2 Aromatic compounds.- 2.1 Introduction.- 2.2 Benzenoids.- 2.3 Coumarins.- 2.4 Isocoumarins, chromanones, chromones and cannabinoids.- 2.5 Macrocyclic lactones.- 2.6 Pyrones, butenolides, lignans and benzofurans.- 2.7 Terphenyls.- 2.8 Flavonoids.- 2.9 Xanthones and benzophenones.- 2.10 Naphthalenes and naphthoquinones.- 2.11 Anthraquinones.- 2.12 Anthracyclines.- 2.13 Some other polycyclic antibiotics.- 2.14 Ansamycins.- References.- 3 Terpenoids.- 3.1 Introduction.- 3.2 Monoterpenoids.- 3.3 Sesquiterpenoids.- 3.4 Diterpenoids.- 3.5 Sesterterpenoids.- 3.6 Triterpenoids.- 3.7 Carotenoids.- References.- 4 Steroids.- 4.1 Introduction.- 4.2 Molecular rearrangement.- 4.3 Remote functionalisation.- 4.4 Photochemical reactions.- 4.5 Partial synthesis.- References.- 5 Amino acids, peptides and proteins.- 5.1 Introduction.- 5.2 Amino acids.- 5.3 Peptides.- 5.4 Techniques for structural elucidation.- 5.5 Proteins.- 5.6 Appendix.- References.- 6 Alkaloids.- 6.1 Introduction.- 6.2 Biomimetic studies.- 6.3 Synthesis.- 6.4 Marine alkaloids.- References.- 7 Nucleosides, nucleotides and nucleic acids.- 7.1 Introduction.- 7.2 Nucleosides.- 7.3 Nucleotides.- 7.4 Nucleic acids.- 7.5 Supplementary reading.- References.- 8 Porphyrins.- 8.1 General introduction.- 8.2 Macrocycle biosynthesis.- 8.3 Haemoprotein model compounds.- 8.4 Porphyrins with easily oxidisable substituents.- 8.5 Utilisation of porphyrin excited states.- 8.6 Porphyrins in photodynamic therapy.- 8.7 DNA-porphyrin interactions.- 8.8 Porphyrins as novel materials.- 8.9 Porphyrins with liquid crystalline properties.- References.- 9 Aliphatic compounds.- 9.1 Introduction.- 9.2 Semiochemicals.- 9.3 Development of synthetic technology.- 9.4 Marine natural products.- 9.5 Enyne-allene and enediyne antibiotics.- References.- Chemical abbreviations and acronyms.
